Mark Ruffalo, known to spill the Marvel Cinematic Universe’s secrets, was at it again, this time, assuring fans of a possible showdown between Spider-Man and an ‘alien’, many think is the famed anti-hero Venom.During an appearance at the Italian Ministry of Public Education, Ruffalo who will be seen sharing screen space with Tom Holland in ‘Spider-Man: Brand New Day’, sent fans into a tizzy when he revealed that their friendy neighbourhood hero could soon face an extraterrestrial threat. “I promise you 1000% that he will be fighting an alien in the future,” Ruffalo told the audience.Mark Ruffalo teases Spider-Man and Venom crossoverThough he did not provide further details or confirm timelines, the confirmation has given way to speculation that Spider-Man will finally encounter Venom, which last saw Tom Hardy in the lead role.Venom and Spider-Man teased in post-credit sceneThe crossover was briefly teased in post-credits scenes of ‘Venom: Let There Be Carnage’ and ‘Spider-Man: No Way Home’ (2021), where Hardy’s Eddie Brock is momentarily transported into the MCU before being sent back to his own universe by Doctor Strange’s spell.While no official announcement has confirmed a Spider-Man and Venom showdown, these speculations have only increased with rumours of Spider-Man tapping into his darker side in the upcoming fourth instalment of the saga.Spider-Man battles aliens in ‘Avengers’ filmsAn alien storyline may also be explored in Holland’s next outing, ‘Spider-Man: Brand New Day’, expected in July 2026. It must be noted that Spider-Man has previously faced off against aliens and even hopped on a spaceship in ‘Avengers: Infinity War’ and ‘Avengers: Endgame’. However, this new rumour has left the door open for the possibility of Spidey finally coming in contact with a symbiote.